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Dose-Response Curve Generator

Sigmoid Emax (Hill) equation with multiple curves

Curves

Example Drugs

Linear Scale

No data – adjust parameters or add curves.

Black dots mark each curve's true EC₅₀ point (baseline + Emax/2) — not a fixed y = 50, since baseline and Emax vary per drug.

Log-Dose Scale

No data – adjust parameters or add curves.

The classic symmetric sigmoid shape only appears on a log concentration axis — this is the standard way dose-response curves are presented.

Hill Equation (Sigmoid Emax Model)

E = E₀ + (Emax·Cⁿ) / (EC₅₀ⁿ + Cⁿ)

  • E₀ (Baseline) — response with no drug present
  • Emax — maximal drug-attributable effect
  • EC₅₀ — concentration producing half of Emax
  • n (Hill coefficient) — steepness of the curve